A new xanthone from the bark extract of Rheedia acuminata and antiplasmodial activity of its major compounds.
نویسندگان
چکیده
Bioassay-guided fractionation of the ethyl acetate bark extract of Rheedia acuminata led to the isolation of the new compound 1,5,6-trihydroxy-3-methoxy-7-geranyl-xanthone, together with four known compounds. These compounds were tested in vitro for their antiplasmodial activity on a chloroquine-resistant strain of Plasmodium falciparum (FcB1) and for their cytotoxicity against the human diploid embryonic lung cell line MRC-5.
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ورودعنوان ژورنال:
- Molecules
دوره 15 10 شماره
صفحات -
تاریخ انتشار 2010